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1250 Mcduff Avenue S

Jacksonville, FL 32205
  • $650,000
  • STATUS: Active
  • ON SITE: 156 Days
  • MLS #: 2129351
UPDATED: 37 min ago
$650,000
  • 2
    BEDS
  • 0.13
    ACRES
  • 2
    BATHS
  • 0
    1/2 BATHS
  • 2,800
    SQFT
  • $232
    $/SQFT
Neighborhood:
Type:
Single-Family Home
Built:
1949
County:
Area:

School Ratings & Info

Description

Owner financing available! Located in the heart of Jacksonville's vibrant Riverside Avondale Historic District, this versatile mixed-use property at 1250 McDuff Avenue South offers a rare opportunity to live, work, or invest in one of the city's most walkable and sought-after neighborhoods. The first-floor commercial space spans approximately 1,800 square feet and allows a wide range of uses by right, including medical or professional office, retail sales, service establishments, and restaurant use--making it ideal for owner-operators or investors seeking flexible income potential. Commercial Neighborhood zoning is scarce in Riverside Avondale, with only three small areas--less than 35 properties total--making this a highly desirable location to operate a business. Upstairs, the residential unit is a charming 2-bedroom, 1 bathroom apartment of roughly 1,100 square feet, featuring hardwood floors and a charming midcentury bathroom that adds character and warmth. The layout is well suited for an owner-occupant, employee housing, or long-term rental. The location creates for a high rental value as it is within walking distance to the Avondale and King Street Shopping Districts, the Riverside Community Garden, Willowbranch Park, and the St. Johns River. The commercial space was leased to long-term tenants at below-market rents, presenting clear upside for future value. Whether you envision a live/work setup, renting one space to offset expenses, or utilizing the full space for one commercial use, the options here are compelling. While located within the historic district, the building itself is not a contributing structure, offering added flexibility for future use. Take advantage of this rare opportunity for a mixed-use property in one of the most desirable neighborhoods in Jacksonville. NOTE: This property is also listed under Commercial MLS #2129365 and Residential Income MLS #2129340

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© 2026 Northeast Florida Multiple Listing Service, Inc. All rights reserved. The data relating to real estate for sale on this web site comes in part from the Internet Data Exchange (IDX) program of the Northeast Florida Multiple Listing Service, Inc. Real estate listings held by brokerage firms other than Beach State Realty are marked with the listing broker’s name and detailed information about such listings includes the name of the listing brokers. Data provided is deemed reliable but is not guaranteed. Data last updated 2026-07-16T21:25:10.797.

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1250 Mcduff Avenue S Jacksonville, FL 32205

  • Price: $650,000
  • Status: Active
  • On Site: 156 Days
  • Updated: 37 min ago
  • MLS #: 2129351
2
Beds
2
Baths
0
½ Baths
0.13
Acres
2,800
SQFT
$232
$/SQFT
1949
Built
Neighborhood:
Avondale
County:
Duval
Area:
032-AVONDALE
Property Description
Owner financing available! Located in the heart of Jacksonville's vibrant Riverside Avondale Historic District, this versatile mixed-use property at 1250 McDuff Avenue South offers a rare opportunity to live, work, or invest in one of the city's most walkable and sought-after neighborhoods. The first-floor commercial space spans approximately 1,800 square feet and allows a wide range of uses by right, including medical or professional office, retail sales, service establishments, and restaurant use--making it ideal for owner-operators or investors seeking flexible income potential. Commercial Neighborhood zoning is scarce in Riverside Avondale, with only three small areas--less than 35 properties total--making this a highly desirable location to operate a business. Upstairs, the residential unit is a charming 2-bedroom, 1 bathroom apartment of roughly 1,100 square feet, featuring hardwood floors and a charming midcentury bathroom that adds character and warmth. The layout is well suited for an owner-occupant, employee housing, or long-term rental. The location creates for a high rental value as it is within walking distance to the Avondale and King Street Shopping Districts, the Riverside Community Garden, Willowbranch Park, and the St. Johns River. The commercial space was leased to long-term tenants at below-market rents, presenting clear upside for future value. Whether you envision a live/work setup, renting one space to offset expenses, or utilizing the full space for one commercial use, the options here are compelling. While located within the historic district, the building itself is not a contributing structure, offering added flexibility for future use. Take advantage of this rare opportunity for a mixed-use property in one of the most desirable neighborhoods in Jacksonville. NOTE: This property is also listed under Commercial MLS #2129365 and Residential Income MLS #2129340
Exterior Features

Architectural Style Other Body Type [] Construction Materials BrickWood Siding Exterior Features [] Fencing [] Lot Features Historic Area Other Structures [] Parking Features GarageOff StreetOn Street Patio And Porch Features [] Pool Features [] Road Surface Type Asphalt Roof Shingle Spa Features [] View [] Waterfront Features [] Waterfront YN No

Interior Features

Appliances DryerElectric RangeRefrigeratorWasher Cooling Central Air Cooling YN Yes Fireplace Features [] Flooring LaminateTileWood Furnished Unfurnished Heating Central Heating YN Yes Interior Features Ceiling Fan(s) Laundry Features In Garage Rooms Total 0

Property Features

Accessibility Features [] Association Amenities [] Association Fee Includes [] Association YN No Attached Garage YN No Cdd Fee YN No Current Use CommercialMixed UseResidential Dpr Eligible YN Yes Electric [] Green Energy Efficient [] Green Water Conservation [] Listing Terms CashConventionalOwner May CarryPrivate Financing Available New Construction YN No Possession Close Of Escrow Property Attached YN No Property Condition [] Property Sub Type Single Family Residence Security Features [] Senior Community YN No Sewer Public Sewer Utilities Cable AvailableElectricity AvailableWater Available Water Source Public Zoning Commercial

Listing courtesy of COWFORD REALTY & DESIGN LLC: 904-330-4733.


© 2026 Northeast Florida Multiple Listing Service, Inc. All rights reserved. The data relating to real estate for sale on this web site comes in part from the Internet Data Exchange (IDX) program of the Northeast Florida Multiple Listing Service, Inc. Real estate listings held by brokerage firms other than Beach State Realty are marked with the listing broker’s name and detailed information about such listings includes the name of the listing brokers. Data provided is deemed reliable but is not guaranteed. Data last updated 2026-07-16T21:25:10.797.

Digital Millennium Copyright Act
 
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